Improved Tolerability Through Gastro-Resistant Softgel Technology

The Science

Doing What Matters, Scientifically.

Improved Tolerability Through Gastro-Resistant Softgel Technology

Targeted Intestinal Release to Minimize Gastrointestinal Irritation

Overcoming the Challenges of Lipid and Essential Oil Supplementation

Traditional oral delivery of concentrated lipids, such as algal DHA or essential oils like peppermint oil, can often lead to upper gastrointestinal side effects. These include "fishy" aftertaste, reflux, heartburn, and nausea, which significantly impact patient compliance. Gastric-resistant (enteric) softgel technology offers a solution by ensuring that the capsule remains intact through the acidic environment of the stomach, only releasing its contents upon reaching the neutral pH of the small intestine.

Precision Delivery for Enhanced Comfort

Compared to standard capsules, gastro-resistant softgels provide a significantly more comfortable experience. By bypassing the stomach, the potent active ingredients — whether they are strong-tasting lipids or concentrated essential oils — never come into contact with the sensitive gastric lining. This practically eliminates the risk of gastric irritation and the unpleasant 'repeating' effect often associated with fish oils or digestive aids.

Anatomical illustration of the digestive system with highlighted intestinal release

Algal DHA: Minimized Sensory Side Effects

Our DHA is derived exclusively from microalgae, providing a marine-origin omega-3 source without fish-derived components. Although algal DHA eliminates concerns related to fishy odor or marine contaminants, premature gastric release of any concentrated lipid can still lead to eructation, reflux, or mild nausea. Gastro-resistant encapsulation prevents early oil liberation in the stomach, thereby reducing aftertaste and lipid reflux. Furthermore, intestinal release aligns with physiological lipid digestion. In the duodenum, bile salts and pancreatic lipase facilitate emulsification and micelle formation, promoting efficient absorption of DHA into enterocytes. This targeted release supports both tolerability and optimal uptake.

Stability and Compliance

Enteric softgels also protect highly unsaturated DHA from acid-mediated stress during gastric transit, helping preserve structural integrity until absorption. Improved gastrointestinal comfort enhances user adherence, particularly in populations requiring sustained intake, such as pregnant and lactating women or individuals using peppermint-based digestive formulations.

In summary, gastro-resistant softgel technology separates gastric exposure from active ingredient release. By delivering peppermint oil and algal DHA directly to the intestine, this approach reduces reflux, irritation, and sensory discomfort while maintaining pharmacological performance. The result is a formulation strategy that prioritizes both efficacy and patient experience.

back to the beginning